Anatomische classificatie
Composite outcome calculators
De COMPOS-panc & COMPOS-panc left calculator
- Composite Outcome Score for Pancreatic Surgery (COMPOS-panc); A Study towards Worldwide Consensus on a Novel Holistic Outcome Score for Pancreatic Surgery
- Publication: under review
Prediction models – ready for use
- Design: international cohort study among 2041 patients with IPMN who underwent pancreatoduodenectomy or left pancreatectomy between 2018 and 2020 in Germany, the Netherlands, Sweden, and the United States.
- Validation: final model demonstrated an AUC of 0.74 for in-hospital/30-day mortality and an AUC of 0.64 for major morbidity.
- Publication: submitted
- Design: International retrospective cohort study conducted within the Trans-Atlantic Pancreatic Surgery (TAPS) Consortium, including all consecutive 2,338 patients with localized PDAC treated with initial FOLFIRINOX.
- Validation: NA
- Publication: Dekker at al, JNCI: Journal of the National Cancer Institute | Oxford Academic march 2026
- Design: Nationwide cohort study among 1257 patients who underwent pancreatoduodenectomy for distal cholangiocarcinoma between 2009 and 2023 in the Netherlands.
- Publication: submitted
- Design: International multicenter study of 383 patients after resection of pancreatic ductal adenocarcinoma following neoadjuvant FOLFIRINOX
- Validation: The AUC was 0.66 for two year survival in the original study and 0.64 in the validation study
- Publication: Rompen et al. Ann Surg. 2025 Jan 31
Predicting endocrine and exocrine pancreatic insufficiency after left pancreatectomy
- Design: Nationwide cohort study among 1157 patients who underwent left pancreatectomy in the Netherlands
- Validation: final model demonstrated an AUC of 0.66.
- Publication: Biesma et al, tbc
Distinguishing pancreatic and periampullary cancer prior to pancreatoduodenectomy
- Design: Nationwide cohort study among 1244 patients who underwent pancreatoduodenectomy between 2014 and 2018 in the Netherlands.
- Validation: final model demonstrated an AUC of 0.88.
- Publication: van Roessel et al, Eur J Surg Oncol 2021
- Design: nationwide cohort study amongst 1693 patients who received surgery for pancreatic ductal adenocarcinoma between 2014-2019 in the Netherlands.
- Validation: Concordance index of 0.66 and calibration slope of 0.99 after internal validation.
- Publication: van Goor et al, Annals of Surgical Oncology 2024
- Design: nationwide cohort study amongst 836 patients who received surgery for pancreatic ductal adenocarcinoma between 2014-2016 in the Netherlands.
- Validation: Concordance index of 0.68 and calibration slope of 0.99 after internal validation.
- Publication: van Goor et al, Ann Surg 2023
- Design: International multicenter retrospective cohort study including 838 patients from 51 centers in 19 countries (2010-2021).
- Publication: van Bodegraven et al, Ann Surg 2023
- Design: data of 118 patients from 1 Dutch center
- Validation: external validation of 57 patients from 1 center in Italy
- Publication: Ingwersen et al – BJS Open 2023
Prediction of biliary etiology in patients with acute pancreatitis
- Design: data of 767 patients from 10 Dutch centers from the prospective observational PWN-CORE registry
- Publication: submitted
Prediction of complications after robotic pancreatoduodenectomy
- Design: data of 235 patients from 1 tertiary center
- Validation: data of 949 patients from 9 international centers
- Publication: Napoli et al, Surgery 2023
- Design: data of 339 patients from 2 Italian centers.
- Validation: internal-external validation of 1336 patient from 5 centers in the United States and the Netherlands
- Publication: De Pastena, van Bodegraven et al, Ann Surg 2022
Intra-operative distal fistula risk score
- Design: data of 339 patients from 2 Italian centers
- Validation: Internal validation was done using bootstrapping
- Publication: De Pastena, Van Bodegraven et al, Ann Surg 2022
- Design: data of 952 patients from 26 center of the European Consortium of Minimally Invasive Pancreatic Surgery (E-MIPS) from 7 countries
- Validation: external validation in a-FRS dataset
- Publication: Mungroop T, et al. Ann Surg 2019
Prediction of 3-years survival in patients after pancreatoduodenectomy for distal cholangiocarcinoma
- Design: data of 454 patients from Dutch Cancer Registry
- Validation: data of 298 patients from Belgian Cancer Registry and 2 centers in 2 countries
- Publication: Belkouz A, Van Roessel S, et al. Br J Cancer 2022
- International validation: data of 3.081 patients from 11 centers in 8 countries
- Publication: van Roessel S, et al. Eur J Surg Oncol 2019
- Design: data of 211 patients from 3 tertiary centers
- Validation: data of 342 patients from 7 international centers
- Publication: Genç C, et al. Annals of Surgery 2018
Prediction of 5-year conditional survival following pancreatectomy for pancreatic cancer
- Design: 3.082 patients from Dutch nationwide registry data
- Publication: Latenstein A, et al. Ann Surg Onc 2020
Prediction model for 3- and 5-year survival in patients with resected ampullary adenocarcinoma
- Design: data of 1.007 patients from 12 centers in 5 countries
- Validation: data of 462 patients from 15 centers in 6 countries
- Publication: Moekotte A, et al. Eur J Surg Oncol 2020
- Design: data of 581 patients from 1 tertiary center
- Publication: Francken M, et al. HPB (Oxford) 2021
- Design and validation: international data from 20 European, 2 US, and 1 Japanese pancreas centers.
- Publication: Klompmaker S, et al. Ann Surg Onc 2018
Old prediction models (updated/validated models above)
Original Fistuala Risk Score (FRS): online calculator
- Design: data from the Dutch Pancreatic Cancer Audit, nationwide registry, and University Hospital Southampton
- Validation: data from the University Hospital Verona and University Hospital of Pennsylvania
- Publication: Mungroop T. et al. Ann Surg 2017
- Design: data from the Academic Medical Center Amsterdam
- Publication: Tol J, et al. Br J Surg 2015